• PREVI® Color Gram

PREVI® Color Gram

A market-leading automated Gram stainer PREVI® Color sprays confidence in your lab!

  • Standardization – slides are all stained the same way
  • Up to 30 slides ready in 5 minutes
  • Eco-friendly system
  • Staining adjustable to your practices/habits
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These days, your microbiology lab faces increased staffing, time and workflow pressures. Yet you can’t let that influence your quality standards: accuracy, time-to-results and full traceability for accreditation. Automated and designed for intuitive workflow, PREVI® Color Gram gives you confidence in the results you provide. It makes Gram staining easy and safe while ensuring accurate, standardized results in minutes.

Accurate standardized staining

PREVI® Color Gram is an automated Gram stainer system that provides accurate, standardized results for all types of specimens.

  • Standardized staining – innovative spray nozzles always
    dispense the same reagent volume
  • No cross contamination – each slide separated & fresh staining reagent used each time
  • Improved microorganism differentiation compared to
    manual and bath staining results
  • Full traceability of reagents, users and maintenance – troubleshoot problems & ensure compliance
  • User management to ensure standardization of the process

Clean and safe staining

Use of hazardous reagents in the Gram staining process is a safety concern, especially when it’s done manually. PREVI® Color Gram has been designed with your safety in mind. And its smart cleaning and disposal features are convenient and environmental responsibility too.

  • User Safety
    • Ready-to-use, closed reagent bottles
    • Integrated reagent waste container to avoid user contact with waste
    • Low toxicity of crystal violet
    • Level sensors avoids waste spillover
  • Clean & convenient
    • Self-contained waste system (no need for a sink)
    • Automated cleaning after 3-hours shut-off
    • Fewer maintenance issues
  • Environmentally Friendly
    • Waste container
    • Less waste: economically uses just enough reagent needed


Intuitive workflow

Your lab is continually being asked to do more with less – so you need to make the most of your time and workflow. Manual Gram staining is a time-consuming, demanding procedure. Previ® Color Gram’s automated, intuitive workflow makes your life easier.

  • Simply Load & Go (just 2 handling steps!)
  • Easy intuitive touch screen
  • Customize & program protocols to suit your needs
  • Rapid results (3-5 minutes)
  • Fully automated process from fixation to slide drying
  • Improved lab workflow with single or batch slides possible
  • Can be integrated with Full Microbiology Lab Automation
  • Convenient, compact system adjusts to your lab

Optional cytocentrifuge function

Get added flexibility and function by turning your PREVI® Color Gram into a full-featured cytocentrifuge system with the ingenious optional PREVI Rotor.

  • Economical (2 instruments in 1!)
  • Safe & reliable with airtight carousel
    • Can be loaded/unloaded under laminar flow hood
  • Flexible:
    • Choose single or dual chambers (expand from 8 to 16 slides)
    • Adjust speed, acceleration rate, time
    • Easy-to-use programmable memory
    • Easily switch between staining & cytocentrifuge


PREVI® Color Gram
Slide carousel capacity 12 (PREVI™ Color Gram 12)
30 (PREVI™ Color Gram 30)
Dimensions H 25.5cm x W 58.5cm x D 56cm
Clearance Height (Lid open) 58cm
Weight 15.5kg
High throughput - 12-120 slides/hour
(PREVI™ Color Gram 12)
- 30-300 slides/hour
(PREVI™ Color Gram 30)


PREVI® Rotor (optional application)
Capacity 8 chambers and slides
Weight 1.1kg
Dimensions Diameter 22.6cm x H6.2cm
Speed Programmable 100 to 200 rpm
Body Fluids Sputum, Pleural Fluids, Synovial/Pericardial Fluids, Bronchial Washing, CSF



  Function Product Name Reference
Primary Stain Crystal Violet 29524
Mordant Iodine 29523
& Counter Stain
Acetone Safranin
Acetone Fuchsin


Please contact your local bioMérieux representative for product availability.

ECCMID 2009 Poster 889

Performance of the PREVI™ Color Gram automated staining system. H. de Montclos, I. Verdier. Laboratory of Microbiology, CH de Bourg-en-Bresse, France


ECCMID 2011 Poster

Efficiency of an automated Gram-staining system for bacteriological diagnostics. Johannes K.-M. Knobloch. Institut für Medizinische Mikrobiologie und Hygiene, Lübeck, Germany


ASM 2011 Poster 2140

Comparison of PREVI™ Color Gram Automated Gram Stain to Manual Gram Stain. D. J. Mayne and J. D. McVay. Sacred Heart Hospital, Pensacola, FL


Customer Testimonials

One of the time-consuming processes in routine microbiology is Gram staining.
In the past our laboratory worked with the classical manual Gram stain method with all the drawbacks you can imagine like labour intensive, preferable batch processing, messy and dirty etc.
Therefore, we wanted to improve this process in our laboratory by introducing PREVI® Color Gram.
Implementing PREVI® Color Gram brought to our organization the improvements we expected like quality improvement, a clean process (closed system) for Gram staining, no more coloration of tables, floors.
PREVI® Color Gram is a user-friendly system providing “ease-of-use” for every employee in our organization and single or batch coloration is no longer an issue.

The Gram stain quality using PREVI® Color is most appreciated by our staff and we have concluded that staining with PREVI® Color is much cleaner and quicker compared to manual coloration. In fact, time to result is decreased.

Implementing PREVI® Color Gram has brought our laboratory the improvement we expected.

Dr M. van Rijn - Medical Microbiologist and Mr Paul Rombouts – Laboratory Manager with their lab team, IKAZIA Hospital, Rotterdam, the Netherlands



For us PREVI® Color Gram has improved the lab’s quality of staining and given us a more standardized technique. We gain in workflow as our work is less interrupted and performed quicker. The instrument is also available 24-hours a day.
PREVI® Color Gram is particularly useful when performing stainings from our BacT/ALERT® bottles since we can clearly and easily differentiate Gram-positive from Gram-negative cells. We have clearly seen an improvement in comparison with our PREVI®ous manual method. Now, we only very rarely have to resort to performing manual gram staining.

Wiga Sokol (on the left), Stine Jorn Christensen (on the right), Department of Microbiology, Skejby, Denmark



We first became interested in PREVI® Color Gram because of the technology used by the instrument and then the demonstration in our lab convinced us to purchase the system.

Since we introduced the PREVI® Color Gram we have faster Gram stains. The Gram staining has become cleaner, we no longer have any cross contamination problems, and we use less reagent volumes.
The quality of the staining with BacT/ALERT samples means we have less crystalization problems and can see the bacteria more easily.

D. Allemeerseh, Cliniques de L’Europe, Brussels, Belgium




One of our Lab goals was to become more “LEAN” and the PREVI® Color Gram helped our Microbiology Department to become more “Lean” and more standardized.

We have always done the manual gram stain which is messy, labor intensive, time consuming and lacks standardization throughout all shifts.

Since we installed the PREVI® Color Gram, we have standardized the gram smears resulting in a clearer and cleaner slide. Along with the main microbiologists, other technologists from other shifts really love this instrument and feel more confident in resulting their gram smear. This was very important as they read “STAT” gram smears and positive Blood Culture smears during the night and it is critical that the smears are stained correctly to give accurate results to a non-Microbiology Technologist.

This instrument provides ease of use, it is user-friendly, and saves time especially with batches of slides to stain. It is a big Quality Improvement since it decreases turn around time to result, clearer smears, and standardized between shifts. This allowed us to become a more “LEAN” Microbiology department.

Joanne Scuderi, Jupiter Medical Center, Jupiter, Florida, USA

Pioneering Diagnostics